Adderall change from xr to sr?

My husband was taking 10mg XR of adderall 1 time a day and lost too much weight so he got discouraged and went switched to 5mg sr 1 time a day. This had no effect at all on him so then he switched to 10mg SR 2x's a day. The change in him is dramatic. He is extremely easy to set off, finds the most ridiculous things to hyper focus on and is a grizzly bear come 8pm. Is there that much of a difference when switching? He has depression, anxiety, eating issues, ADD, emotional issues and the XR I thought was working great. But his PCP scared him when he went for his physical and he just stopped it for 3 weeks. Mind you, the PCP never once mentioned seeing a dietician or getting his life long eating issues at hand since the benefits in his mood with adderall were so great. He now is seeing a dietician and has alerts on his phone to eat and is adding many more calories per day. He is just so different on the SR that Im confused. Any advice?